Arousal is the body's physical and emotional response to sexual stimulation, which can include increased blood flow to the genitals, lubrication, and heightened sensitivity. Arousal and desire are related but distinct, and either can be affected by health changes.

Neuropathy is damage to peripheral nerves that can cause numbness, tingling, pain, or reduced sensation, often in the hands, feet, or genital area. Because it can change how touch is experienced, it may call for adjusting the type or intensity of stimulation.

Libido is a person's overall sexual desire or interest in sexual activity. It naturally varies over time and can be influenced by hormones, medications, stress, relationships, health conditions, and mood.